Bioplatforms Australia Press Release
Melanoma Framework Data Initiative – Nature Publication
Collaboration and infrastructure key
in improving survival rates from Melanoma.
Melanoma in Australia represents a major, unsolved public health challenge. It remains one of the leading cancer killers, especially of young and middle-aged adults. This is partly because prognosis remains poor and largely unpredictable for all but early stage disease, and there are essentially no effective treatments for advanced disease. The underlying biology of the
disease, and its lack of response to traditional cancer therapies is poorly understood. However recent studies of melanoma has provided proof of principle in identifying possible novel therapeutic targets for treating this disease through genomic analysis.
A project to create large-scale Systems Biology datasets to allow cell biology to be undertaken in a systematic and comprehensive manner was first proposed to Bioplatforms Australia (BPA) by a joint team from the Queensland Institute of Medical Research (QIMR), Westmead Millennium Institute (WMI) and Melanoma Institute Australia (MIA). With a view to ensuring the proposed framework data would be supported, in an enduring and accessible state, using multiple research communities with multiple research agendas, BPA undertook a broader consultation involving stakeholders from various institutions and States. Parties now involved in this project comprise a broad collaboration of leading Australian scientists and institutions including MIA, WMI, QIMR, University of Sydney, Western Australian Institute of Medical Research, Australian National University John Curtin School, Peter MacCallum Cancer Centre and others.
BPA led the working groups responsible for Communications and co-investment; Sampling, design, ethics and data; and Informatics (storage, accessibility and privacy issues). The management and accessibility of the project data
“The tissue resource from this collaborative project has created the largest repository of melanoma tissue and linked data in the world. Data from this resource sets the standard for melanoma clinical and pathologic research, such as setting criteria for
Project results were recently published in Nature. BPA’s support enabled the first
Robust collaboration and
For more information on the Melanoma Framework Data Initiative visit: http://www.bioplatforms.com/melanoma/
To view the finding from the Melanoma Framework Data Initiative visit: https://www.nature.com/nature/journal/vaop/ncurrent/full/nature22071.html
This press release can be downloaded here: Melanoma Framework Data Initiative – Nature Publication 2017.
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